Abstract
Since from its clinical introduction to the present time, measurement of serum Prostate Specific Antigen (PSA) level is one of the most widely used tests in urology practice. Initially, the upper limit for PSA was 4 ng/mL, but today, a reduction for the upper limit is recommended to 2.5-3 ng/mL for patients between 60 and 65 years and younger. On the use of PSA as a screening test for prostate cancer, there are differences of opinion. However, it is a recommended test in the evaluation and monitoring of the risky group for prostate cancer. All in all, together with a good patient information, PSA test should be performed at appropriate intervals for appropriate people with an appropriate age.