Abstract

Introduction: The aim of this studying was to evaluate urine culture results and to determine quinolone

resistance rates on patients with lower urinary tract infection symptoms who attended to urology outpatient

clinics.

Materials and Methods: Urine culture results retrospectively were examined on patients with lower

urinary tract infections who attended to Çanakkale Military Hospital Urology Outpatient Clinics between

January 2004 and June 2006. Urine cultures, which caused the growth of various bacteries, were examined for

antibiotic sensitivity and resistance.

Results: During the studying period 200 community urine samples of which 57 have grown bacterial

isolates were analyzed. Among the total of 57 isolates, 27 (47.4%) were E.coli, 14 (24.6%) Clebsiella, 10

(17.5%) gram (-) bacilles, 1 (1.7%) S.aureus, 1 (1.7%) Proteus and 1 (1.7%) Pseudomonas. The range of

susceptibility of bacteries to Trimethoprim-sulphamethoxasol was 43.8%, to ceftriaxone 73.7%, to ampicilline

43.8%, to cefuroxime axetil 61.4%, to ofloxacine 64.9%, to ciprofloxacine 66.7% and to nitrofurantoin 49.1%

during the testing period. The range of susceptibility of E.coli species to Trimethoprim-sulphamethoxasol was

59.25%, to ciprofloxacine 74%, to ofloxacine 70%, to ampicilline 55.5%, to cefuroxime aksetil 74%, to

ceftriaxone 77.8% and to nitrofurantoine 100% were determined during the studying period. Among these 57

patients, 38 were female and 19 were male.

Conclusion: Because of antibiotic resistance have been growing recently, using the empirical antibiotic

should be given up. If we will use empirical antibiotics, we shouldn’t choose quinolones in simple lower

urinary tract infection without any intervention. We should prefer nitrofurantoine for these patients, instead

of them.