Abstract

After achieving toilet training bed wetting without any known reason is called as primary monosymptomatic nocturnal enuresis. Theories upon etiology are many and the therapy modalities are not well known. Bladder capacity is well related with enuresis. Desmopressin that is an antidiuretic hormone analog is one of the agents used to treat this disease. With this study the expected and functional bladder capacities and their relation with the results of desmopressin therapy are evaluated. We aimed to find the criteria to be used while choosing the right enuretic patient for desmopressin therapy.

35 patients diagnosed as primary monosymptomatic nocturnal enuretic were given 20 μgm intranasal desmopressin once a day for four weeks. At the end of the fourth week all patients were grouped as treated and non-treated according to their flow charts. The results then evaluated with expected and functional bladder capacities of all patients.

68 % of the patients were found to be dry at the end of the treatment. Among this group the patients whose functional bladder capacities were 70% or more than the expected bladder capacity were the best-As a conclusion primary monosymptomatic enuretic patients whose functional bladder capacities are 70 % more than their expected bladder capacities are good candidates for desmopressin treatment.