Primary adenocarcinoma of the seminal vesicles: a phantom tumor

Primary adenocarcinoma of the seminal vesicles (ASV) is a very rare neoplasm with less than 50 histologically confirmed cases reported in the literature. The diagnosis is complex and is based on a combination of immunohistochemical, clinical and radiological findings. Biopsy is not always conclusive, and surgical resection is usually required to determine whether the tumor originated from the seminal vesicles. We present a case of primary ASV that was discovered upon investigation of inguinal lymphadenopathy. A history of recent hormonal manipulation for the treatment of infertility may be associated with the development or the progression of this rare tumor.