Urology Research & Practice
PEDIATRIC UROLOGY - Original Article

Long-term Functional, Sexual, and Cosmetic Outcomes in Adult Patients Who Underwent Hypospadias Repair During Childhood at a Highly Specialized Italian Pediatric Hospital


Department of Urology, University of Cagliari, Santissima Trinità Hospital, Cagliari, Italy


Department of Urology, University of Florence, Careggi Hospital, Florence, Italy


Department of Pediatric Urology, University of Florence, Meyer Children Hospital, Florence, Italy

Urol Res Pract 2024; 50: 127-133
DOI: 10.5152/tud.2024.24005
Read: 155 Downloads: 69 Published: 30 May 2024

Objective: This study aims to evaluate long-term functional, sexual, and cosmetic outcomes in adult patients who underwent hypospadias repair during childhood at a national highly specialized pediatric hospital.

Methods: Medical records of pediatric patients who had undergone surgical repair of hypospadias between 1993 and 2004 at Meyer Children Hospital of Florence were reviewed. Adult patients were contacted by telephone between July and August 2021 and invited to participate. Long-term surgical outcomes were assessed focusing on complications and reinterventions, and 3 validated questionnaires on urinary function, erectile function, and penile cosmetic appearance were administered.

Results: From January 1993 to December 2004, a total of 799 patients with hypospadias underwent repair surgery. Two hundred thirty-nine patients gave consent to be included in the study. Follow-ups occurred between 17 and 28 years after the first surgery. Most patients had anterior localization of hypospadias (210/239) and associated penile curvature (132/239). The most frequent surgery for hypospadias repair was meatal advancement and glanduloplasty incorporated (MAGPI) (88/239), and the most used surgical treatment for penile curvature was the Nesbit technique (49/132). The complication rate was 27% (65/239) in an average time of 4.7 years, and 48 surgical procedures have been performed to treat them. At follow-up, the mean IPSS was 0.96 ± 1.97, the mean IIEF-5 score was 24.10 ± 1.02, and the mean HOSE score was 15.47 ± 0.45. Patients who underwent reintervention reported a lower IPSS than those who underwent only 1 surgery (0.29 vs. 1.16).

Conclusion: Hypospadias repair during childhood leads to rather normal urinary and sexual function and penile cosmetic appearance in adolescence and adulthood.

Cite this article as: Bocchino AC, Cocci A, Pezzoli M, et al. Long-term functional, sexual, and cosmetic outcomes in adult patients who underwent hypospadias repair during childhood at a highly specialized Italian Pediatric Hospital. Urol Res Pract. 2024;50(2):127-133.

EISSN 2980-1478