Abstract

The aim of this prospective study is to researcli the freguency of voiding dysfunctions and alteration in urodynamics parameters such as postvoiding residual urine volume (PVR), maximum urine flow rate (Omax) and maximum cystometric bladder capacity in children and adolescents with hyperthyroidism.

The study included 13 patients aged range from 5.5 years to 18 years old, mean age was 11.2 years, 9 female and 4 male. After diagnosis of hyperthyroidism, patients and/or their parents were guestionnaired about voiding dysfunction symptoms and then PVR, Omax and maximum cystometric bladder capacity were performed in all patients. After acguired euthyroidism with antithyroid treatment, all patients and/or their parents were repeated.

After euthydroidism acguired, all patients, except one who had posterior urethral valve, were symptoms free, and mean PVR and maximum cystometric bladder capacity reduced from 48.75 ml and 433.33 ml to 5.83 ml and

355.83 ml respectively, and mean Omax increased from 14.11 ml/sec to 20.45 ml/sec. These all alterations in urodynamic parameters were statistically significant(p<0.001).

In conclusion, we think that the fregueney of voiding dysfunctions be increased, urodynamics parameters such as PVR, Omax and maximum cystometric bladder capacity be changed, and all these changes be reversible in children and adolescents with hypertyroidism. Therefore, thyroid hormone disorders especially hyperthyroidism should be borne in mind when patients present with unexplained voiding dysfunctions.